Toshinari Takamura Selected Research

Alcoholic Fatty Liver

10/2019	Serum C16:1n7/C16:0 ratio as a diagnostic marker for non-alcoholic steatohepatitis.
3/2017	Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model.
6/2015	Response to Importance of confounding factors in assessing fatty acid compositions in patients with non-alcoholic steatohepatitis.
3/2009	The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis.
7/2008	Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects.
9/2005	cDNA microarray analysis of autoimmune hepatitis, primary biliary cirrhosis and consecutive disease manifestation.

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Toshinari Takamura Research Topics

Disease

55	Insulin Resistance 10/2023 - 02/2003
40	Type 2 Diabetes Mellitus (MODY) 11/2023 - 06/2005
25	Non-alcoholic Fatty Liver Disease 05/2024 - 01/2007
19	Obesity 11/2023 - 12/2005
12	Fibrosis (Cirrhosis) 05/2024 - 01/2007
12	Fatty Liver 05/2024 - 01/2007
11	Inflammation (Inflammations) 05/2024 - 11/2007
9	Hyperglycemia 02/2023 - 04/2007
8	Neoplasms (Cancer) 05/2024 - 01/2005
7	Liver Cirrhosis (Hepatic Cirrhosis) 02/2024 - 11/2006
7	Glucose Intolerance 05/2021 - 01/2007
7	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2009 - 06/2003
6	Alcoholic Fatty Liver 10/2019 - 09/2005
5	Body Weight (Weight, Body) 11/2023 - 01/2012
5	Atherosclerosis 10/2023 - 12/2003
5	Cardiovascular Diseases (Cardiovascular Disease) 02/2023 - 10/2019
5	Albuminuria 11/2020 - 04/2002
5	Diabetic Nephropathies (Diabetic Nephropathy) 05/2015 - 04/2002
3	Weight Loss (Weight Reduction) 11/2023 - 02/2010
3	Overweight 02/2023 - 05/2018
3	Osteoporosis 01/2022 - 01/2007
3	Heart Failure 01/2021 - 06/2005
3	Neoplasm Metastasis (Metastasis) 01/2012 - 01/2008
2	Muscular Atrophy (Muscle Atrophy) 01/2023 - 01/2023
2	Cushing Syndrome 12/2022 - 01/2010
2	Familial Hypophosphatemic Rickets (X-Linked Hypophosphatemia) 01/2022 - 09/2021
2	Hepatitis 08/2021 - 09/2005
2	Diabetes Mellitus 11/2020 - 10/2018
2	Weight Cycling 01/2020 - 01/2016
2	Disease Progression 07/2019 - 06/2017
2	Starvation 01/2019 - 05/2014
2	Myocardial Infarction 03/2018 - 02/2010
2	Myocardial Ischemia (Ischemic Heart Diseases) 03/2018 - 02/2010
2	Hepatocellular Carcinoma (Hepatoma) 03/2017 - 03/2013
2	Overnutrition 01/2016 - 01/2012
2	Proteinuria 05/2015 - 11/2013
2	Chronic Hepatitis C 10/2012 - 09/2005

Drug/Important Bio-Agent (IBA)

36	Glucose (Dextrose)FDA LinkGeneric 02/2024 - 01/2007
27	Insulin (Novolin)FDA Link 01/2023 - 02/2003
19	Selenoprotein PIBA 01/2023 - 11/2010
14	Proteins (Proteins, Gene)FDA Link 02/2024 - 11/2010
9	Fatty Acids (Saturated Fatty Acids)IBA 11/2023 - 11/2007
7	Biomarkers (Surrogate Marker)IBA 01/2024 - 10/2012
7	Messenger RNA (mRNA)IBA 12/2021 - 03/2009
7	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 07/2008
6	EnzymesIBA 11/2023 - 02/2003
6	Chemotactic FactorsIBA 12/2021 - 05/2014
6	Triglycerides (Triacylglycerol)IBA 07/2017 - 01/2007
6	LipidsIBA 01/2012 - 06/2004
5	AlbuminsIBA 08/2021 - 10/2012
5	empagliflozinIBA 01/2021 - 04/2017
5	Pioglitazone (Actos)FDA Link 12/2010 - 06/2005
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2008 - 12/2003
4	Alanine Transaminase (SGPT)IBA 05/2024 - 09/2005
4	Sodium-Glucose Transporter 2 InhibitorsIBA 11/2023 - 04/2017
4	Metformin (Glucophage)FDA LinkGeneric 01/2021 - 01/2012
4	Sitagliptin Phosphate (Januvia)FDA Link 01/2018 - 01/2015
4	Short-Acting InsulinIBA 01/2018 - 03/2007
4	Plasminogen Activator Inhibitor 1IBA 03/2013 - 12/2003
3	IsotopesIBA 10/2023 - 07/2019
3	SodiumIBA 10/2023 - 02/2020
3	CholesterolIBA 04/2023 - 11/2007
3	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2023 - 03/2013
3	Somatostatin Receptors (Somatostatin Receptor)IBA 12/2022 - 01/2012
3	Sodium-Glucose Transport ProteinsIBA 01/2022 - 04/2017
3	SeleniumIBA 01/2021 - 11/2018
3	Glucagon (Glukagon)FDA Link 02/2020 - 03/2007
3	Arginine (L-Arginine)FDA Link 07/2019 - 03/2007
3	AdiponectinIBA 01/2012 - 11/2007
3	DNA (Deoxyribonucleic Acid)IBA 11/2010 - 02/2003
2	6- ((4- ethylphenyl)methyl)- 3',4',5',6'- tetrahydro- 6'- (hydroxymethyl)spiro(isobenzofuran- 1(3H),2'- (2H)pyran)- 3',4',5'- triolIBA 11/2023 - 01/2022
2	glimepiride (Amarel)FDA LinkGeneric 10/2023 - 01/2022
2	UbiquitinIBA 01/2023 - 01/2023
2	Adrenocorticotropic Hormone (ACTH)FDA Link 12/2022 - 01/2005
2	CytokinesIBA 01/2022 - 12/2003
2	Intrinsic Factor FDA Link 01/2022 - 01/2020
2	Phosphates (Orthophosphate)IBA 01/2022 - 09/2021
2	CarbohydratesIBA 10/2021 - 05/2016
2	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 10/2021 - 01/2014
2	Antiviral Agents (Antivirals)IBA 08/2021 - 04/2019
2	CreatinineIBA 11/2020 - 05/2015
2	fibroblast growth factor 21IBA 01/2020 - 05/2018
2	AntioxidantsIBA 01/2020 - 11/2007
2	palmitoleic acidIBA 10/2019 - 02/2015
2	somatostatin receptor 2IBA 10/2018 - 01/2012
2	Octreotide (Sandostatin)FDA LinkGeneric 10/2018 - 01/2012
2	Insulin-Like Growth Factor I (IGF-1)IBA 10/2018 - 01/2012
2	Phosphotransferases (Kinase)IBA 03/2018 - 03/2013
2	Insulin Aspart (NovoLog)FDA Link 01/2018 - 06/2012
2	A-Form DNA (A-DNA)IBA 01/2018 - 12/2008
2	Branched-Chain Amino AcidsIBA 03/2017 - 10/2012
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017 - 09/2014
2	Hypoglycemic Agents (Hypoglycemics)IBA 01/2016 - 03/2007
2	Hemoglobins (Hemoglobin)IBA 01/2016 - 11/2013
2	Pravastatin (Pravachol)FDA LinkGeneric 05/2015 - 09/2008
2	Atorvastatin (Lipitor)FDA Link 05/2015 - 09/2008
2	Raloxifene Hydrochloride (Evista)FDA Link 03/2013 - 01/2007

Therapy/Procedure

18	Therapeutics 01/2023 - 03/2006
6	Glycemic Control 11/2019 - 02/2010
2	Diet Therapy (Therapy, Diet) 01/2016 - 05/2015